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Overexpression of -ECS in Arabidopsis also enhanced GSH, though less markedly (Xiang et al., 2001)

Dimercaprol (British anti-Lewisite) is used to treat heavy metal toxicity, especially that of arsenic

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In 1978 and 1990, the first intracellular delivery of mRNA and its delivery in murine models were achieved, respectively [5, 6, 9]

The case of NAC encapsulates the core challenges of MIRI therapy: while its mechanism of enhancing endogenous defenses is conceptually superior to direct scavenging (as argued in Section 2.3), its clinical potential is ultimately nullified by the formidable practical hurdles of delivery and timing required to counteract the rapid and localized oxidative burst (Section 2.1)

Meanwhile, ipamorelin is investigated for its potential effects through ghrelin-related pathways