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Of the natural bioactive compounds discussed, fewer than 30% have been evaluated in adequately powered randomized controlled trials in human DKD populations

Endocrine disrupting chemicals can be divided into two groups: persistent organic pollutants (POPs) and non-persistent EDCs (npEDCs) Table 1

Moreover, p53 plays a role in modulating cellular metabolism and influences the progression of ocular disorders such as DR through its influence on blood glucose regulation and fatty acid metabolism (86)

Maternal Selenium, Copper and Zinc Concentrations in Early Pregnancy, and the Association with Fertility

These cause chromatin condensation and transcriptional repression in adaptation to stress (Vincent et al., 2022)

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