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In laboratory settings it has been studied alongside NAD+ pathway components to assess downstream effects on mitochondrial function

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doi:10.1146/annurev.nutr.19.1.217
For more information on detecting and diagnosing deficiency, see our article: Vitamin B12 Deficiency Test Vitamin B12 Deficiency Symptoms in the Nervous System B12 deficiency is associated with the following neurological symptoms

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