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doi: 10.3389/fphar.2017.00155

Resistance mechanisms include Met amplification (~5% of cases) [4] and more frequently (50% of cases) an additional T790M gatekeeper mutation within the EGFRm [58]

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PMID: 15155329 DOI: 10.1213/01.ANE.0000113544.21754.A5 Osta WA et al (2010): Nicotinic Acetylcholine Receptor Gene Expression Is Altered in Burn Patients

Both studies met the primary endpoint of treatment success as determined by a score of clear or almost clear on the validated Investigator Global Assessment-Atopic Dermatitis scale, alongside a two-grade improvement at four weeks

PMC 8163657