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This mitochondrial gridlock is the biochemical basis for post-exertional malaise (PEM), the hallmark symptom of ME/CFS where patients experience a devastating crash in physical and cognitive function after minor exertion

Since dietary fibers are not absorbed, their effects would be associated directly in the intestine and indirectly in the overall system by the action of their fermentation products
Our Guide for the Care and Use of Laboratory Animals meets United States regulations which are according to the Assessment and Accreditation of Laboratory Animal Care International (AAALAC) accreditation

Author contributions MK, TB, JH, MM, LH, KK, RP, and SK designed and carried out experiments

2024;38 Suppl 3:3-11

Co-Q10 and the amino acid arginine have been shown to affect blood thinning and negatively interact with warfarin in some cases
