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In darbepoetin alfa, enhanced half-life is also attributed to its increased sialic acid content, making clearance mediated by asialoglycoprotein receptors (found in liver cells) less favorable 66

Babetto, E., Wong, K

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doi: 10.2143/AC.62.4.2022278

About obesity Obesity is a serious chronic, progressive, and complex disease that requires long-term management.4-6 One key misunderstanding is that this is a disease of just lack of willpower, when in fact there is underlying biology that may impede people with obesity from losing weight and keeping it off.4,6 Obesity is influenced by a variety of factors, including genetics, social determinants of health, and the environment.7,8 About Novo Nordisk Novo Nordisk is a leading global healthcare company founded in 1923 and headquartered in Denmark