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Patients with high NNMT levels tend to have poor prognostic parameters and overall survival (OS) and disease-free survival (DFS) (26, 27, 45)

Thus, people consuming plant-based diets are at an increased risk of suffering from a deficiency of this vital nutrient

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Another therapeutic strategy for kidney or liver diseases is increasing NAD + production by inhibiting ACMSD in the de novo NAD + synthesis pathway 235,301

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