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The interconnection between amino acid sensing and insulin signaling encompasses intricate interactions

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The ability of these chemicals to induce ferroptosis will also be discussed with special attention paid to their effects in SH-SY5Y human neuroblastoma cells since these cells possess properties of dopaminergic neurons, and, therefore, have a long history of use as an in vitro model in studies on PD (Cheung et al., 2009)

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CD44 is a transmembrane glycoprotein and surface receptor for hyaluronan involved in the mutual response between cells and their microenvironment (49) (Fig

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In the 1980 s, researchers observed the coexistence of global hypomethylation and promoter hypermethylation of specific genes in cancer cells, thereby linking epigenetic dysregulation to tumorigenesis [10]

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Interestingly, this effect is augmented by the presence of hyperglycemia, indicating that comorbid diabetes may enhance the proatherogenic phenotype of G6PD-d

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To identify the AngIV that may be involved in the AD, we first detected the level of AngIV in WT and APP/PS1 mice

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