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Funding This trial was supported by grants from Medical Research Council of Southeast Sweden (numbers 479961, 656241 and 854911) and Capio Research Foundation, Sweden (numbers 2018-3195 and 2019-3277)

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3.2.4 Intestinal changes and bone health While we do not know of any study directly linking the effect of aging on gut barrier-to-bone signaling, the intestinal changes that occur with aging are associated with bone loss in other conditions