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10.1152/ajplung.00253.2002

Circulating levels of IGF-1 appear to play a major role in bone remodeling and have a direct impact on linear bone growth, as shown by various skeletal parameters evaluated in this study

Bypassing it is not just a pharmacokinetic trick

Ascorbic acid is probably more familiar to you as Vitamin C

doi: 10.1158/1078-0432.CCR-15-2218

Theyre also a practical choice since theyre more accessible and affordable
