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A total of 176 articles were removed following the exclusion criteria and because they did not meet inclusion criteria due to lack of a controlled design, not meeting the setting characteristics or not meeting the review objective

Li et al., 2024b)

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Metabolic reprogramming induced by glutamine metabolism Unsurprisingly, glutamine metabolism plays a critical role in tumor progression since it not only supports mitochondrial oxidative phosphorylation but also supplies metabolic intermediates for the TCA cycle, glutathione synthesis, and NEAA synthesis and simultaneously produces NADPH 157159