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However, B12 deficiency can lead to several problems, some concerning nerve damage that might become permanent

Three weeks after the surgery, both 2nd and 3rd MEPs waves-related latencies in the nerve wrapping group were significantly shorter than those in the control group (p = 0.0207 and 0.0271, respectively)

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Reported side effects have mostly been mild: transient injection-site reactions, occasional headaches, or mild flu-like symptoms

Future studies should deal with the impact of this approach in different tumour sites and their secondaries, address the wide variations in tumour behavior caused by intratumor heterogeneity and focus on the potential complications of promoting neovascularization, such as the risk of significant/life threatening bleeding, and its safety in vascular diseases