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6 Synergistic mechanisms and combination therapies 6.1 Chemo-curcumin nano-delivery systems Synergistic therapy utilizing nanoparticle co-delivery systems represents a pivotal advancement in enhancing curcumins anticancer efficacy by leveraging complementary mechanisms with conventional chemotherapeutics

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In alveolar type II (L2) cells, EpRE motif in the proximal region of GP5 EpRE induces the expression of the major GGT transcript mRNA V-2 in the lung (38)

Eur J Biochem 270(16):33353344 Slominski A, Pisarchik A, Zbytek B, Tobin DJ, Kauser S, Wortsman J (2003) Functional activity of serotoninergic and melatoninergic systems expressed in the skin

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Maintenance of redox homeostasis typically involves the delicate regulation of ROS by redox systems, with evidence that the glutathione (GSH/GSSG), thioredoxin and cysteine/cystine redox systems are differentially modulated under dynamic and non-equilibrium redox conditions [16]