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high dose dominated glutathione low dose oxidation Several lines of antioxidant defense against oxidative stress: antioxidant enzymes, nanomaterials with multiple enzyme-mimicking activities, and low-molecular-weight antioxidants Targeting oxidative stress in disease:
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Hear Res 344: 265274, 2017

doi: 10.1038/ncb3341 8 ChioIICJafarnejadSMPonz-SarviseMParkYRiveraKPalmWet al

Separately, searches in the OMIM, GeneCards, and DisGeNET databases identify 5,069 genes associated with NSCLC, while the FerrDb database provides a list of 484 human genes related to ferroptosis

10.1038/s41568-019-0216-7 111 HuD.YangC.LokC

Indeed, iron is a strong promoter of oxygen radical species that can drive the oxidation of proteins, lipid peroxidation and nucleic acid modifications [2]
