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[DOI] [PMC free article] [PubMed] [Google Scholar] 104.Mangerich A., Burkle A

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In addition, evaluating inhibitory tonus as a measure of repressed plasticity in the post-injured brain, concomitant changes in the excitatory input may occur, making it difficult to estimate changes in the overall excitatory/inhibitory balance of the neural circuits undergoing rearrangement

This review provides a comprehensive summary of different mechanisms involved in hyperpigmentation and gives a clear guide to topical active ingredients with clinical evidence