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Elevated intracellular GSH levels blocked bortezomib-induced nuclear factor erythroid 2-related factor 2 (NFE2L2, NRF2)-associated stress responses, including upregulation of the xCT subunit of the Xc- cystine-glutamate antiporter

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Therefore, HEP-1 has the potential to preserve the integrity of the gastric mucosa and is anticipated to be a key bioactive ingredient in the prevention and repair of GMI.

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It is commonly used in naturopathy for its ability to bind heavy metals, thus facilitating their removal from the body

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