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In vitro investigations often evaluate gene expression patterns, structural protein synthesis markers, and enzymatic activity related to extracellular matrix dynamics

Nevertheless, conflicting views persist regarding the precise mechanistic pathways driving liver injury, with earlier reports emphasizing apoptosis, caspase-independent cell death, the ubiquitin-proteasome system, or ROS involvement [54]

We present how mitochondrial dysfunction, through impaired bioenergetics, oxidative stress, defective quality control, and altered dynamics, can drive neuronal cell loss

The low level of CoQ10 contributes to mitochondrial dysfunction and the generation of ROS and lipid peroxidation [1113]

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Association of cortical macrostructural and microstructural changes with cognitive performance and gene expression in subcortical ischemic vascular disease patients with cognitive impairment