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Different mechanisms of internalization of IONPs at cellular level have been proposed, such as clathrin-mediated endocytosis, caveolae-mediated endocytosis or receptor-mediated endocytosis, among others (169, 187189)

Additionally, we discovered that a GSH threshold of 10.2 nmol/mg effectively differentiates resistant cells from sensitive cells, with an AUC of 0.913, providing a robust distinction between chemotherapy-resistant and sensitive patients

2017;8:CD006612

(2022) 10:goab053

Apart from these reports, Lei G et al