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[DOI] [PMC free article] [PubMed] [Google Scholar] 83.Rimessi A., Previati M., Nigro F., Wieckowski M.R., Pinton P

409 We also demonstrated that mild elevation of mitochondrial biogenesis regulator PGC1 in late-generation telomerase-deficient mice was sufficient to attenuate metabolic compromise and extending health span

B12 supports brain health and mood regulation

Id say the effect lasted about 24 hours
Saffron extract and crocin exert anti-inflammatory and anti-oxidative effects in a repetitive mild traumatic brain injury mouse model

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