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Description
Vitiligo is characterized by an imbalance between the production of ROS and the capacity of the antioxidant defense system, leading to increased oxidative damage within melanocytes

The cellular health approach differs from targeting individual symptoms or pathways

J Biol Chem 291, 7527-40 Bordes, P., Sala, A.J., Ayala, S., Texier, P., Slama, N., Cirinesi, A.M., Guillet, V

There are a variety of parameters that can be used for monitoring cell viability

Apple flavonol quercetin has been shown to lower systolic blood pressure, improve endothelial function, and lessen the risk of cardiovascular disease (585587)

Overexpression experiments show increased GSH levels and greater resistance to oxidative stress, while knockdown or disease-associated mutations make cells more susceptible to redox imbalance [12,71,72]
