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2 Vyzulta also has better 24-hour efficacy compared with timolol, which is crucial for elevated nocturnal IOP, indicated by the CONSTELLATION study

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10.1210/edrv-7-3-314 [DOI] [PubMed] [Google Scholar] 167.Johnsen KB, Moos T

10.1172/jci26373 158 ZambonF.CherubiniM.FernandesH

doi: 10.1074/jbc.M111.261578

As indicated below, different combinations of the M and H subunits generate LDH isoforms in different tissues
