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Furthermore, our data indicate that neuronal GHS-R deletion regulates genes mediating central thermogenic activation in ventromedial hypothalamus (VMH), paraventricular nucleus (PVN) and lateral hypothalamus (LH), implying elevated sympathetic outflow to brown adipose tissue and beige subcutaneous adipose tissues 9

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Also known as a Jarisch Herxheimer reaction, this type of reaction was discovered when two dermatologists, Adolph Jarisch and Karl Herxheimer found that some individuals undergoing an antibiotic regimen for syphilis started to experience a skin reaction in response (1)

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Here are some of the most common causes of each: Hives : Food, medication, insect bites or stings, or other substances can cause allergic reactions