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Experientia (1981) 5

[DOI] [PMC free article] [PubMed] [Google Scholar] [35].Wang B, Yee Aw T, Stokes KY

By masking the thiol, the protein will be altered in its capacity to form disulfide bonds and to fold into different functional (perhaps active) conformations

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Additionally, multiobjective optimization methods such as reinforcement learning 271 and Bayesian optimization 272 can help to create formulations that optimize aerosol performance, mucus penetration and cellular uptake at the same time
