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Cellular-level effects begin within hours of administration

Evers A, Verhoeven E, Kraaimaat F, De Jong E, De Brouwer S, Schalkwijk J, Sweep F, Van De Kerkhof P (2010) How stress gets under the skin: cortisol and stress reactivity in psoriasis

As 2 O 3 induces apoptosis in human hepatocellular carcinoma HepG2 cells through a ROS-mediated mitochondrial pathway and activation of caspases
