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Hydroxocobalamin should be taken as a preventative measure against complications that arise from vitamin b12 deficiencies, high homocysteine levels, and methylation issues

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Prog Neurobiol (2011) 95:4967.10.1016/j.pneurobio.2011.07.001 13 AlbistonALPeckGRYeatmanHRFernandoRYeSChaiSY

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Sensitivity to cold : Feeling cold in the hands and feet, even in warm environments

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Essential role of insulin receptor substrate 1 (IRS-1) and IRS-2 in adipocyte differentiation

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This approach can be further developed into real-time decision-support systems in clinical settings, where physicians dynamically adjust treatments based on patient responses

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