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For instance, silica nanoparticles (Nano-SiO2) significantly reduce NO levels and eNOS activity by activating the PI3K/Akt/mTOR signaling pathway, increase inflammatory responses, activate autophagy, and ultimately lead to ECD (Zhu et al., 2011)

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3.3 Antitumor effects of cannabimimetic agents The patterns of hematopoietic and tumor cells development are affected by cannabimimetic substances

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The structure of apo protein-tyrosine phosphatase 1B C215S mutant: more than just an S O change

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M.GibsonE

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