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While oxygen is necessary for cholesterol synthesis, GBM cells can obtain cholesterol from the microenvironment under hypoxic conditions (54, 58)

In this study, we showed that Tim-AIII suppressed cell proliferation and migration, induced G2/M phase arrest and ultimately triggered cell death of non-small cell lung cancer (NSCLC) cell lines accompanied by the release of reactive oxygen species (ROS) and iron accumulation, malondialdehyde (MDA) production, and glutathione (GSH) depletion

BhattacharyaKDeyRSenDPaulNBasakAKPurkaitMPet al

FTL, Ferritin light chain

Both stimulate growth hormone release, but they operate through different receptor mechanisms and have distinct pharmacokinetic profiles

Inhibition of ferroptosis has been found to dampen the ability of M