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[DOI] [PMC free article] [PubMed] [Google Scholar] Nakka S, Jugulam M, Peterson D, Asif M

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However, there is still a lack of research to solidify this drugs position in the treatment of IBD, especially after mixed results achieved in phase 3 study (LAUREL), where contrary to earlier findings, no significant differences were observed between etrolizumab maintenance treatment and placebo for the primary endpoint of remission [58]

During periods of stress, excessive amounts of oxygen can release free iron from ferritin, triggering the Fenton reaction, which creates OH