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In TNF-stimulated mouse cardiac muscle cells, sodium hydrosulfide ameliorated the impaired mitochondrial respiration and ATP production/synthesis, and attenuated excess oxidative stress, which might be due to the enhanced expression of metabolic indices such as CPT1

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10.1016/j.jcmgh.2022.01.007 127 MooliR

In the six clinical studies with a control group, including the only randomized controlled study [74,77,79,80,82,84], PTX was used in combination with other treatments (multi-modal or combination therapy), and in all of these studies, this therapeutic approach was effective and able to achieve excellent statistically significant results

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