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Among these, the NOD-, LRR-, and pyrin domain-containing 3 (NLRP3) inflammasome plays a significant role in APAP-induced liver injury

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Furthermore, elevated levels of inflammatory and oxidative stress markers, such as TGF- and VEGF, suggesting that inflammation plays a critical role in disease progression (319, 320)

This can occur during physical activity, environmental pollution, certain diseases, drug or nicotine use

Reduced motivation, fatigue, and cognitive impairments hinder compliance with necessary diabetes care practices, such as glucose monitoring, dietary adherence, and maintaining physical activity, which may exacerbate hyperglycemia and increases complication risks [127]