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Evidence suggests that the equivalent of a vicious cycle can occur where microglia produce oxidative products and then increased intracellular reactive oxygen species (ROS), in turn, activates a redox-sensitive NF-B to provoke excessive neuroinflammation
doi: 10.1152/ajpcell.2001.281.6.C1964
K.et al (2016)
Bhatti JS, Bhatti GK, Reddy PH (2017) Mitochondrial dysfunction and oxidative stress in metabolic disordersa step towards mitochondria based therapeutic strategies
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