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Immune cells like macrophages and potentially factors released from nerves within the lesions can also contribute pro-fibrotic signals [112]

Mesencephalic astrocyte-derived neurotrophic factor (MANF) mitigates protein oxidation and restores phagocytosis mediated by E3 ligase activity, thereby promoting the survival of BC cells under glucose starvation [106]

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Open Access Library Journal (2022) 9:e9414