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For the last two decades, skeletal muscle was the main target of therapy [40], and drug discovery programs focused on strategies to inhibit the muscle catabolic pathways and stimulate the anabolic pathways [52]

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In spite of this, decreases in omega-6 fatty acid levels were observed in our study, as previously reported, which support the usefulness of EPA administration

Annu rev Nutr 18:39-61, 1998.