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Similar content being viewed by others Introduction Major depressive disorder (MDD), a main cause of disability worldwide, is characterized by physical changes such as tiredness, weight loss, and appetite loss

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[DOI] [PubMed] [Google Scholar] 27.Wilsman NJ

In addition, oxidative stress induced by hyperglycemia modulates sirtuin-mediated epigenetic modifications by affecting sirtuin expression and activity (117)

Saturated long-chain fatty acids activate inflammatory signaling in astrocytes

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