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Quando vengono applicati topicamente, penetrano negli strati superficiali dellepidermide e interagiscono con specifici recettori cellulari, soprattutto quelli presenti nei fibroblasti

The major efficacy outcome measure was overall survival and additional efficacy outcome measures were time to disease progression, overall response rate, and response duration

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PKC Isozyme S-Cysteinylation by Cystine Stimulates the pro-Apoptotic Isozyme PKCdelta and Inactivates the Oncogenic Isozyme PKCvarepsilon