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The restoration of normal oxygen level during reperfusion causes a release of cytokines and chemokines from activated tissue-resident macrophages and infiltration of pro-inflammatory neutrophils 26

[DOI] [PMC free article] [PubMed] [Google Scholar] 14.Perelman MA, Rowland DL

Therefore, mitochondrial dysfunction is a key contributor to aging and various age-related diseases, including neurodegenerative, cardiovascular, and metabolic disorders (Fig

American Society of Mechanical Engineers, 2013, p

10.1007/s12602-018-9411-1 9 BoutagyN