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Description
Muscle aches occurred in 3.7-7.7% versus 1.6-2.2% on placebo

10.1590/S0037-86822012000600010 Rev

Journal of Pharmacy and Pharmacology , 53 (10), 1393-1401

Pharmacology of calcineurin antagonists

The C terminal also gets fully protonated and uncharged at this pH which augments the aggregation process

N.BaruaC
