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doi: 10.1016/j.ijheh.2011.03.001

The tradeoff is tighter dosing precision

10.3390/cells8091065 9 BehrendL.HendersonG.ZwackaR
Oxygen is a fundamental substance for maintaining the normal functions of neurons, but its delicate metabolism can be a source of more or less toxic molecular derivatives, and it can affect biological molecules such as proteins, nucleic acids and membrane lipids (Figure 2)

Other compounds, such as glycolytic inhibitors, carbohydrate and lipid absorption blockers, polyamines, and polyphenols, which collectively modulate pathways regulating the effects of free radicals, are also under consideration

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