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WNT and beta-catenin signalling: diseases and therapies
The study assessed plasma lipid profile, oral glucose tolerance (OGTT), and whole-body insulin sensitivity by hyperinsulinemic-euglycemic clamp procedure
Based on receptor-mediated targeting, BDPR NSs can effectively cross the BBB, target dopaminergic neurons, specifically clear ROS and reduce iron aggregation in PD lesions, and exhibit good neuroprotective effects in PD cell, nematode, and mouse models (226)
Howland, W
Hence, it is now urgent to discover new, effective and safe strategies to prevent and/or treat this hardly bearable condition
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