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coli endotoxin, IL-1beta and TNF-alpha on antioxidant status of cultured hepatocytes

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mTORC1 inhibition, which results in decreased 4E-BP1 phosphorylation, reduces the intracellular pool of free eIF4E, promoting its defective compartmentalization to polysomes attached to the rER membrane, which causes retarded translation

Keep enough time for processing, travel, and any clinical questions that may need clarification