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Patient Scenario 1 A 77-year-old female with a history of intrahepatic cholangiocarcinoma, hypertension, and stage IV kidney disease with an estimated glomerular filtration rate (eGFR) of 22 who was diagnosed after routine laboratory examinations showed elevated alkaline phosphatase and total bilirubin 3.4 mg/dL

All patients underwent a thorough history-taking and physical examination, including testicular volume assessment

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