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The EDTA solution had been previously de-aerated with nitrogen gas

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The SPIONs and the quantum dots used in the formulation have a size of ~20 nm and ~8 nm, respectively, and the hydrodynamic diameter of the final liposome was determined to be ~100 nm

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found that histidine catabolism affects the sensitivity of cells to methotrexate, and dietary supplementation of histidine maintains a suitable chemotherapy effect with a low dose of medication

In turn, hindered patient adherence and overall drug efficacyparticularly among elderly patientsare noted [27]