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Thus, these reports not only reveal a novel ferroptosis surveillance system, the CoQ/FSP-1 system but also solve the long-existing mystery as to why CoQ (CoenzymeQ, ubiquinone), an essential component of the mitochondrial electron transfer chain (ETC), is also located in extramitochondrial spaces where CoQ function was not known (Morr and Morr, 2011)

Secondly, it is known that the process of cell death is an extremely complicated interconnected process involving multiple molecules

In addition, glutathione can chelate metal ions (such as copper) that are essential cofactors for tyrosinase, further contributing to a skin whitening mechanism at the enzymatic level

Hidalgo-Carcedo, C

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doi: 10.1039/c9fo01014a Summary Keywords gastric cancer, oxidative stress, signaling pathways, pathophysiology, therapeutic targets Citation Liu Y, Shi Y, Han R, Liu C, Qin X, Li P and Gu R (2023) Signaling pathways of oxidative stress response: the potential therapeutic targets in gastric cancer