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Mol Cell Endocrinol (2020) 500:110631

Malaguarnera et al (42) demonstrated that in patients with minimal hepatic encephalopathy, acetyl-L-carnitine improved the quality of life by reducing serum albumin levels

The GLP-1R, present in glutamatergic neurons in hypothalamic nuclei such as the arcuate nucleus and the paraventricular nucleus (PVN), contributes to the increased hepatic FGF21 most likely via direct autonomic nervous system circuits from the brain to the liver

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