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Adjunctive therapies, including selenium and vitamin D supplementation, have shown modest benefit

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[DOI] [PubMed] [Google Scholar] 20.An S.S., Bai T.R., Bates J.H., Black J.L., Brown R.H., Brusasco V., Chitano P., Deng L., Dowell M., Eidelman D.H., et al

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The updated proposal includes autophagy as another hallmark owing to its relevant role in regulating other hallmarks, such as DNA repair and nutrient sensing/metabolism [220]