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10.1016/j.freeradbiomed.2013.05.001 125 StarkovA

Research Gate: Relationships between Hair Melanization, Glutathione Levels, and Senescence in Wild Boars

cerevisiae strain DSY5 38 (Genotype MATa leu2 trp1 ura3-52 his3 pep4 prb1) was transformed with the Ycf1 expression construct and a 50 mL primary culture grown for at least 24 h at 30 C with shaking at 200 rpm in SC-His media (0.67% w/v yeast nitrogen base without amino acids, 2% w/v glucose, and 0.08% w/v amino acid dropout mix without histidine)

It potently inhibited c-Met phosphorylation and c-Met-dependent proliferation, migration, or invasion of human tumor cells in vitro (IC 50 values, 520 nmol/L)

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First, parkin can directly recycle oxidized glutathione (GSSG) under rising ROS conditions, generating one reduced GSH molecule, which in turn results in the S- glutathionylation of parkin itself (P-SH + GSSG \(\to\) P- S- SG + GSH) (Figs