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It is common to not include people who are on medications that can affect the immune system, including oral corticosteroids, disease-modifying antirheumatic drugs (DMARDs), biologics, and cancer treatment (chemotherapy, radiation, immunotherapy) in vaccine clinical trials

Additionally, Pantiora et al

Integrating structured dietary protocols into microbiota-based therapies offers a practical strategy to reinforce gut-thyroid axis stability, enhance intervention outcomes, and support long-term disease management

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Moreover, in recent years, many minimally invasive or noninvasive techniques have been incorporated into AR, such as microbubble-assisted ultrasound, which combines ultrasound with microbubbles in the middle ear, and the new magnetic/acoustic dual-controlled microrobot, which can efficiently transport medications to the inner ear without damaging the ear tissues, making the treatment and rehabilitation of hearing impairment more effective (Yi et al., 2024

[] Histopathologically, the transition from neurofibroma to MPNST is characterized by nuclear atypia, loss of neurofibroma architecture, high cellularity, and increased mitotic activity