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increases the removal of LDL and intermediate-density lipoprotein cholesterol (IDL) from plasma Rapidly enhances the clearance of thyroid hormone (Figure 1)

Modulation of Vigilance in the Primary Hypersomnias by Endogenous Enhancement of GABAA Receptors. Science Translational Medicine, vol

Protein Eng Des Sel 32(2):67-76 2019 PMC6908819 Jesinkey SR, Madiraju AK, Alves TC, Yarborough OH, Cardone RL, Zhao X, Parsaei Y, Nasiri AR, Butrico G, Liu X, Molina AJ, Rountree AM, Neal AS, Wolf DM, Sterpka J, Philbrick WM, Sweet IR, Shirihai OH, Kibbey RG

2019 Sep

Lancet 2014

Aging accelerates ferroptosis in hepatocytes, and metabolic stressors such as high cholesterol, obesity, and diabetes can exacerbate this cell death program, leading to increased liver injury