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Interestingly, an emerging body of evidence suggests that micro RNAs (miRNAs, small non-coding RNAs involved in the post-transcriptional regulation of gene expression) could be putative biomarkers for detecting neurodegeneration Thus, recent reviews have shown that some miRNAs are differentially associated with AD by modulating the expression of important genes involved in A production (e.g., BACE1 ) or inflammation (Goodall et al., 2013

The brain contains elevated levels of 7nAChR in regions associated with cognitive function and memory, such as the hippocampus, hypothalamus, colliculi, geniculate nuclei, thalamus, cortex, medial habenula, and amygdala ( Fig

Neurodegenerative Disorders Neurons are highly dependent on G6PD and the PPP to combat ROS [15]

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