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Mechanizmy angiogenezy nowotworowej

403405 Furthermore, PERK may also share other modes of activation with IRE1, such as direct binding to unfolded proteins 437 or an altered lipid composition of the ER membrane

This disruption alters localized lipid metabolism and cholesterol trafficking, detrimentally modifying membrane composition and further crippling mitochondrial integrity [44]

In addition, we plan to further explore the potential differences in the metabolic effects of different fat sources on the ketogenic diet in subsequent studies to more comprehensively assess the contribution of fat composition to the ketogenic diet